For a liquid flowing through a tube at constant velocity, the distance from the point of origin can provide a measure of the reaction time. This concept of continuous flow, first applied over a century ago to follow biochemical reactions by absorption spectroscopy, is now being used in conjunction with high-resolution structural methods such as X-ray crystallography and cryo-electron microscopy. The resultant kinetic information is crucial to understanding the mechanism.
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Clive R. Bagshaw; A beginner's guide to flow kinetics. Biochem (Lond) 1 April 2020; 42 (2): 40–44. doi: https://doi.org/10.1042/BIO04202001
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