The chances are that you'll have heard something about sildenafil -- marketed under the trade name ViagraTM (Figure 1). Launched in 1998 as a tablet for treating male erectile dysfunction (MED), it's now been used by over 15 million men and has attracted plenty of publicity. As a biochemist however, you'll probably want to go one step further. This review will take a closer look at the interesting biochemical details of how sildenafil works.

This content is only available as a PDF.