Chromatography is the most commonly used analytical technique in laboratories world-wide, with HPLC initial systems set to reach sales worth $259 million by 2005. The demand for HPLC columns is driven largely by the need to comply with America's Federal Drugs Administration's 21 CFR Part 11 regulations, and new sales of liquid chromatography (LC)-MS to the pharmaceutical sector, which remains the main industry sector and outlet for sales of HPLC solutions. The main driver influencing the purchase of LC-MS has been the need by companies to replace existing units to meet all the requirements for electronic record-keeping and to enable greater compatibility with data systems. The demand for upgrades has therefore been sustained, as standardization of IT systems has not been forthcoming.

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