For decades, the circadian system of animals was viewed as a single or a few centralized structures driving all overt physiological circadian rhythms. Recent data have questioned this view and have revealed a much more complex and dynamic picture. We now know that circadian oscillators are also present in many different tissues and constitute part of a hierarchical circadian system. In this article, we describe this multi-oscillator system that constitutes the basis for the variety of physiological rhythms.
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Feature| February 01 2004
Central and peripheral oscillators in mammals: A guided tour through a network of clocks
Biochem (Lond) (2004) 26 (1): 23–25.
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Fabienne Guillaumond, Nicolas Cermakian; Central and peripheral oscillators in mammals: A guided tour through a network of clocks. Biochem (Lond) 1 February 2004; 26 (1): 23–25. doi: https://doi.org/10.1042/BIO02601023
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