The transport of proteins across membranes has been characterized in detail in Bacteria and Eukarya. Very little, however, is known about this process in the third domain of life, the Archaea. In recent years a number of groups have started to explore this area of research, but at present most information is derived from genomic sequences. Here, two of the main protein transport pathways found in archaea are briefly discussed and compared to bacterial and eukaryal systems.

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