Prions are remarkable infectious agents that cause fatal neurodegenerative diseases in humans and other mammals. There is increasing activity, but, as yet, limited success, in the search for therapeutic compounds that can be used to treat these diseases. This is, in part, because a number of significant problems exist, hampering the route to rational drug screening strategies.
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Feature| August 01 2005
The search for a cure: Prion eliminating compounds
Biochem (Lond) (2005) 27 (4): 24–28.
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Lee J. Byrne, Mick F. Tuite; The search for a cure: Prion eliminating compounds. Biochem (Lond) 1 August 2005; 27 (4): 24–28. doi: https://doi.org/10.1042/BIO02704024
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