Iduron is a dedicated glycosaminoglycan (GAG) company situated at the University of Manchester in the Paterson Institute for Cancer Research. The principlal scientific finding that underpinned the formation of Iduron were two papers published in the early 1990s from the laboratories of Avner Yayon and Alan Rapraeger that revealed that the glycosaminoglycan heparan sulfate (HS) was essential for the efficient transmembrane signalling and mitogenic activity of acidic and basic fibroblast growth factor (aFGF and bFGF; now known as FGF1 and FGF2 respectively), the two prototypic members of the FGF family of growth and migration factors.

This content is only available as a PDF.