Although cancer treatment has developed considerably in the 21st century, there are still 8–9 million people dying of this disease each year. One strategy, using a patient's own immune system to combat their cancer, has recently led to a significant improvement in survival rates. The concept of immunotherapy is not new; as far back as 1893, William Coley reported tumour regression following repeated injections of bacterial toxin from Streptococcus pyogenes in a patient with advanced sarcoma. Over 100 years later, the use of cancer vaccine has come a long way, with a better understanding of the immune system's interaction with the tumour microenvironment.
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Feature| February 01 2019
Cancer vaccine: how far are we from curing cancer?
Biochem (Lond) (2019) 41 (1): 12–15.
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Ruhul Choudhury, Lindy Durrant; Cancer vaccine: how far are we from curing cancer?. Biochem (Lond) 1 February 2019; 41 (1): 12–15. doi: https://doi.org/10.1042/BIO04101012
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