Biological rhythmicity has relevance to almost every aspect of our lives, from sleep-wake cycles and everyday metabolism, to physical and mental health implications. We experience jet lag because our biological clocks can only shift by a certain amount, treatment for which has been explored but is perhaps not as effective as we thought. This issue explores the molecular and wider regulation of these rhythms in mammals, plants and insects, and the behavioural effects we see as a result. We hope you enjoy this issue.

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