Human face transplantation is now a clinical reality. This new treatment has long captured the interest and imagination of scientists, the media and the public. This is not surprising since, like no other part of our anatomy, we associate our face with so many qualities that make us uniquely human. It is this great importance we attach to our face that makes facial disfigurement such a devastating condition. Of all the physical handicaps, none is more socially devastating than facial disfigurement, which often leads to depression, social isolation, and even suicide 1 .