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Depletion of mitochondrial inorganic polyphosphate (polyP) in mammalian cells causes metabolic shift from oxidative phosphorylation to glycolysis.

Plasmodium falciparum Atg18 localizes to the food vacuole via interaction with the multi-drug resistance protein 1 and phosphatidylinositol 3-phosphate

Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: Insights into plasticity of substrate binding and activation

Inositol pyrophosphates promote MYC polyubiquitination by FBW7 to regulate cell survival

Abiological Catalysis by Myoglobin Mutant with a Genetically Incorporated Unnatural Amino Acid

Current Issue

Volume 478,

Issue 7,

April 16, 2021

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Chair of the Editorial Board

Mark Lemmon

Yale University School of Medicine, USA

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Exploring the molecular mechanisms that underpin key biological processes, the Biochemical Journal has been at the forefront for over 100 years

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With so many journals to choose from in the field of biochemistry alone, previous Chair of the Editorial Board, David Carling, talks about why you should submit your paper to the Biochemical Journal.

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Led by Professor Mark Lemmon, the Biochemical Journal Editorial Board is made up of leaders in the field from across the globe

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Open access articles

Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: Insights into plasticity of substrate binding and activation

Plasmodium falciparum Atg18 localizes to the food vacuole via interaction with the multi-drug resistance protein 1 and phosphatidylinositol 3-phosphate

Depletion of mitochondrial inorganic polyphosphate (polyP) in mammalian cells causes metabolic shift from oxidative phosphorylation to glycolysis.

Structural basis of the human Scribble–Vangl2 association in health and disease

Review articles

Mitochondrial genome stability in human: understanding the role of DNA repair pathways

Organismal roles for the PI3Kα and β isoforms: their specificity, redundancy or cooperation is context-dependent

Principles and practice of determining metal–protein affinities

Protein tyrosine phosphatases in cell adhesion

Commentaries

A new degree of complexi(n)ty in the regulation of GLUT4 trafficking

Deaminated purine bypass by DNA polymerase η

T cells: a dedicated effector kinase pathways for every trait?

Two routes of direct intercellular communication in brain cancer