1. Administration of sinapic acid to the rat results in the excretion of 3-hydroxy-5-methoxyphenylpropionic acid, dihydrosinapic acid, 3-hydroxy-5-methoxycinnamic acid and unchanged sinapic acid in the urine. The sinapic acid conjugate sinalbin is also catabolized to free sinapic acid and 3-hydroxy-5-methoxyphenylpropionic acid in the rat. 2. 3,4,5-Trimethoxycinnamic acid is metabolized in part to sinapic acid and 3-hydroxy-5-methoxyphenylpropionic acid. 3. 3,5-Dimethoxycinnamic acid is metabolized to 3-hydroxy-5-methoxycinnamic acid and 3-hydroxy-5-methoxyphenylpropionic acid. 4. The metabolic interrelationships of these compounds were studied by the administration of intermediates and a metabolic pathway is proposed. 5. The metabolism of the corresponding benzoic acids was studied, but these compounds and their metabolites were shown not to be intermediates or products of the metabolism of the related cinnamic acids.
Skip Nav Destination
Follow us on Twitter @Biochem_Journal
Article navigation
July 1969
-
Cover Image
Cover Image
- PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
Research Article|
July 01 1969
Metabolism of sinapic acid and related compounds in the rat
L. A. Griffiths
L. A. Griffiths
1Department of Biochemistry, University of Birmingham, P.O. Box 363, Birmingham 15
Search for other works by this author on:
Publisher: Portland Press Ltd
© 1969 The Biochemical Society
1969
Biochem J (1969) 113 (4): 603–609.
Citation
L. A. Griffiths; Metabolism of sinapic acid and related compounds in the rat. Biochem J 1 July 1969; 113 (4): 603–609. doi: https://doi.org/10.1042/bj1130603
Download citation file:
Sign in
Don't already have an account? Register
Sign in to your personal account
You could not be signed in. Please check your email address / username and password and try again.
Could not validate captcha. Please try again.
Biochemical Society Member Sign in
Sign InSign in via your Institution
Sign in via your InstitutionGet Access To This Article
Cited By
Follow us on Twitter @Biochem_Journal
Open Access for all
We offer compliant routes for all authors from 2025. With library support, there will be no author nor reader charges in 5 journals. Check here |
![]() View past webinars > |