1. 2-Amino-1-naphthyl hydrogen sulphate can be rapidly isolated from the urine of dogs dosed with 2-naphthylamine by precipitation with cetylpyridinium bromide. 2. No evidence was obtained for the presence of 2-naphthylhydroxylamine-O-sulphonic acid, noteworthy as a possible source of the carcinogens, 2-naphthylhydroxylamine and 2-amino-1-naphthol. 3. Treatment of neutral persulphate oxidations of 2-naphthylamine with the reagent gave only the cetylpyridinium salt of 2-amino-1-naphthyl hydrogen sulphate.
Isolation of 2-amino-1-naphthyl hydrogen sulphate with cetylpyridinium bromide from metabolic and chemical oxidations of 2-naphthylamine
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D. Manson; Isolation of 2-amino-1-naphthyl hydrogen sulphate with cetylpyridinium bromide from metabolic and chemical oxidations of 2-naphthylamine. Biochem J 1 September 1970; 119 (3): 541–546. doi: https://doi.org/10.1042/bj1190541
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