1. An enzyme in extracts of mammalian tissues catalyses the hydrolysis of d-myoinositol 1:2-cyclic phosphate (an intermediary in the enzymic degradation of phosphatidylinositol) to produce d-myoinositol 1-phosphate. 2. The enantiomorph of the substrate is not attacked. 3. The pH optimum is about 8.1–8.3 and the reaction is stimulated by Mg2+ ions. 4. Extracts from rat kidney cortex and medulla are very rich sources of the enzyme; brain, testis and small intestine contain intermediary activities, and other tissues contain very small amounts.
Skip Nav Destination
Research Article| March 01 1972
d-myoInositol 1:2-cyclic phosphate 2-phosphohydrolase
R. M. C. Dawson ;
Biochem J (1972) 127 (1): 113–118.
- Views Icon Views
- Share Icon Share
R. M. C. Dawson, N. Clarke; d-myoInositol 1:2-cyclic phosphate 2-phosphohydrolase. Biochem J 1 March 1972; 127 (1): 113–118. doi: https://doi.org/10.1042/bj1270113
Download citation file:
Don't already have an account? Register
Get Access To This Article
Buy This Article