A disease of Angus cattle previously known as pseudolipidosis has been shown to be an inherited lysosomal storage disease, in which an oligosaccharide containing mannose and glucosamine is the storage substance. Diseased animals have a near-absolute deficiency of the lysosomal enzyme, α-mannosidase, whereas heterozygotes have a partial deficiency of this enzyme. The condition is analogous to the human disease known as mannosidosis.
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Research Article| June 01 1972
Deficiency of α-mannosidase in Angus cattle. An inherited lysosomal storage disease
J. D. Hocking ;
R. D. Jolly ;
Biochem J (1972) 128 (1): 69–78.
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J. D. Hocking, R. D. Jolly, R. D. Batt; Deficiency of α-mannosidase in Angus cattle. An inherited lysosomal storage disease. Biochem J 1 June 1972; 128 (1): 69–78. doi: https://doi.org/10.1042/bj1280069
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