Cholinesterases are inhibited by 2-fluoro-1,3,2-dioxaphosphorinane 2-oxide by a mechanism that involves a slow association step followed by a very slow phosphorylation step. No phosphorylation step was observed for the interaction between acetylcholinesterase and 2-S-[2′-(NN-diethylamino)ethyl]thio-1,3,2-dioxaphosphorinane 2-oxide.
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Research Article| June 01 1976
Inhibition of acetylcholinesterase by derivatives of 1,3,2-dioxaphosphorinane 2-oxide
Biochem J (1976) 155 (3): 717–719.
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D B Coult; Inhibition of acetylcholinesterase by derivatives of 1,3,2-dioxaphosphorinane 2-oxide. Biochem J 1 June 1976; 155 (3): 717–719. doi: https://doi.org/10.1042/bj1550717
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