Ferritin was purified from the serum of two patients with idiopathic haemochromatosis. The protein contained three types of subunit--the H and L subunits of tissue ferritins (although only a trace of H could be detected) and a third subunit, ‘G’, with the highest apparent molecular weight. Only the ‘G’ subunit band stained for carbohydrate, indicating that a proportion of the subunits of human serum ferritin are glycosylated. Although serum was obtained from patients with idiopathic haemochromatosis, it is probable that the ‘G’ subunit is a component of normal serum ferritin.
Research Article| December 01 1981
Detection of a glycosylated subunit in human serum ferritin
Biochem J (1981) 199 (3): 565–571.
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S J Cragg, M Wagstaff, M Worwood; Detection of a glycosylated subunit in human serum ferritin. Biochem J 1 December 1981; 199 (3): 565–571. doi: https://doi.org/10.1042/bj1990565
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