Adipose-tissue lipogenesis and fatty acid uptake in vitro were higher in obese than in lean Zucker rats aged 10 days. On average, insulin stimulated each of these two metabolic pathways to the same extent in both genotypes. However, in fa/fa pups, we observed that insulin stimulation decreased when adipose-tissue weight increased.
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© 1984 London: The Biochemical Society
1984
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