The antigenicity of the N-terminal region of skeletal-muscle actin was analysed. Two epitopes, corresponding to the 1-7 and 18-28 sequences, were determined. The antibodies specific for the first epitope discriminate skeletal-muscle actin from cardiac-muscle and smooth-muscle actins. The antibodies specific for the second epitope interact with all the actins tested, ranging from invertebrate to higher-vertebrate actins.
Structural variations in actins. A study of the immunological reactivity of the N-terminal region
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C Roustan, Y Benyamin, M Boyer, J C Cavadore; Structural variations in actins. A study of the immunological reactivity of the N-terminal region. Biochem J 1 January 1986; 233 (1): 193–197. doi: https://doi.org/10.1042/bj2330193
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