1. The fluorescent fatty acid probe 11-(dansylamino)undecanoic acid binds to rat liver fatty acid-binding protein with a 1:1 stoichiometry. 2. The binding of the fluorescent probe is competitive with long-chain fatty acids. 3. Binding displacement studies were performed with a wide range of fatty acids and other ligands and identified C16 and C18 fatty acids as the preferred fatty acids for rat liver fatty acid-binding protein. No preference was observed for unsaturated fatty acids within this group. 4. Fatty acyl-CoA binds less well than the corresponding fatty acid.
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Research Article| October 15 1987
Studies on fatty acid-binding proteins. The binding properties of rat liver fatty acid-binding protein
T C Wilkinson ;
Biochem J (1987) 247 (2): 485–488.
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T C Wilkinson, D C Wilton; Studies on fatty acid-binding proteins. The binding properties of rat liver fatty acid-binding protein. Biochem J 15 October 1987; 247 (2): 485–488. doi: https://doi.org/10.1042/bj2470485
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