Comparison of amino acid sequence data suggested that there may be a functional relationship between the staphylococcal epidermolytic toxins and V8 proteinase. The hypothesis was tested by treating epidermolytic toxin with di-isopropyl phosphorofluoridate, which bound specifically at serine-195, the homologue of the active-site serine residue of V8 proteinase.
Research Article| July 15 1990
The reactive serine residue of epidermolytic toxin A
C J Bailey;
Biochem J (1990) 269 (2): 535-537.
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C J Bailey, T P Smith; The reactive serine residue of epidermolytic toxin A. Biochem J 15 July 1990; 269 (2): 535–537. doi: https://doi.org/10.1042/bj2690535
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