A modified way to construct kinetic barrier diagrams is presented. Although the diagram superficially resembles a free-energy profile, it is independent of any conception derived from transition-state theory. Some simple calculations referring to the lactate dehydrogenase turnover reaction at equilibrium demonstrate self-consistency of the diagram and its direct relevance to the results of numerical simulations of the detailed course of enzyme-catalysed reactions.
Research Article| May 15 1991
How to draw kinetic barrier diagrams for enzyme-catalysed reactions
Biochem J (1991) 276 (1): 265–268.
- Views Icon Views
- Share Icon Share
- Cite Icon Cite
J Südi; How to draw kinetic barrier diagrams for enzyme-catalysed reactions. Biochem J 15 May 1991; 276 (1): 265–268. doi: https://doi.org/10.1042/bj2760265
Download citation file: