Plastids are a diverse group of essential organelles in plants that include chloroplasts. The biogenesis and maintenance of these organelles relies on the import of thousands of nucleus-encoded proteins. The complexity of plastid structure has resulted in the evolution of at least four general import pathways that target proteins into and across the double membrane of the plastid envelope. Several of these pathways can be further divided into specialty pathways that mediate and regulate the import of specific classes of proteins. The co-ordination of import by these specialized pathways with changes in gene expression is critical for plastid and plant development. Moreover, protein import is acutely regulated in response to physiological and metabolic changes within the cell. In the present review we summarize the current knowledge of the mechanism of import via these pathways and highlight the regulatory mechanisms that integrate the plastid protein-trafficking pathways with the developmental and metabolic state of the plant.
Review Article| June 12 2008
Protein trafficking to plastids: one theme, many variations
Danny J. Schnell
Danny J. Schnell 1
*The 21st Century Centers of Excellence Program, Cryobiofrontier Research Center, Iwate University, Ueda 3-18-8, Morioka 020-8550, Japan
†Department of Biochemistry and Molecular Biology and Programs in Plant and Molecular and Cellular Biology, University of Massachusetts, Amherst, MA 01003, U.S.A.
1To whom correspondence should be addressed (email firstname.lastname@example.org).
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Takehito Inaba, Danny J. Schnell; Protein trafficking to plastids: one theme, many variations. Biochem J 1 July 2008; 413 (1): 15–28. doi: https://doi.org/10.1042/BJ20080490
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