Adipose tissue was initially considered an inert connective tissue filled with lipid that provided a supportive function in the body. This dull depiction of adipose tissue began to shift when studies during the 1950's supported the idea that adipose tissue was an active organ that could store excess energy [1]. Subsequently, work from 1960's established white adipose tissue (WAT) not only as a storage depot, but as an active site for the mobilization of energy in the form of fatty acids [2]. In contrast, brown adipose tissue (BAT), initially described as a gland-like organ [3], is a highly oxidative organ that can burn fatty acids to generate heat. The classification into brown and white is simplistic as adipose tissue is a highly plastic organ that can greatly expand...

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