1. The specific radioactivity of [14C]glycerol released during the incubation of brown fat with [14C]glucose is much greater than that of the tissue lipid glycerol. 2. From a study of the release of [14C]glycerol from pre-labelled brown fat, it is concluded that the tissue contains a pool of glycerides with a higher rate of turnover than those in the main lipid store. 3. This pool contains newly synthesized glycerides, has a half-life of 25–30min and supplies about 25% of the glycerol liberated by brown fat. 4. Thus, a significant fraction of the total14C incorporated from glucose into brown-fat lipids is released as [14C]glycerol during an incubation.
Research Article|July 01 1971
Evidence for the presence of a pool of glycerides with a rapid rate of turnover in brown fat from newborn rabbits
Biochem J (1971) 123 (4): 485-491.
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B. L. Knight; Evidence for the presence of a pool of glycerides with a rapid rate of turnover in brown fat from newborn rabbits. Biochem J 1 July 1971; 123 (4): 485–491. doi: https://doi.org/10.1042/bj1230485
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