1. [3α-3H]Cholesta-7,9-dien-3β-ol is converted in high yield into cholesterol by a 10000gav. supernatant fraction of rat liver homogenate. 2. Incubation of cholesta-7,9-dien-3β-ol with [4-3H]NADPH and rat liver microsomal fractions under anaerobic conditions resulted in3H being incorporated into the 14α-position of cholest-7-en-3β-ol. 3. Under anaerobic conditions in the absence of NADPH cholesta-7,9-dien-3β-ol was isomerized into cholesta-8,14-dien-3β-ol by rat liver microsomal fractions.
A novel olefinic rearrangement. The enzymic conversion of cholesta-7,9-dien-3β-ol into cholesta-8,14-dien-3β-ol
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M. Akhtar, C. W. Freeman, A. D. Rahimtula, D. C. Wilton; A novel olefinic rearrangement. The enzymic conversion of cholesta-7,9-dien-3β-ol into cholesta-8,14-dien-3β-ol. Biochem J 1 September 1972; 129 (2): 225–229. doi: https://doi.org/10.1042/bj1290225
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