Standard methods of glycosaminoglycan separation were used to confirm the presence of hyaluronic acid in sheep and rabbit articular cartilage. During incubation of carilage in vitro in the presence of [1-14 C]acetate, cartilage cells synthesize this macromolecule and, under the conditions used, it appears to have a shorter turnover time than chondroitin suplhate in the same tissue. The possible functions of hyaluronic acid in cartilage are discussed.
Research Article|February 01 1975
The synthesis of hyaluronic acid by sheep and rabbit articular cartilage in vitro
G C Gillard;
Biochem J (1975) 145 (2): 209-213.
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G C Gillard, B Caterson, D A Lowther; The synthesis of hyaluronic acid by sheep and rabbit articular cartilage in vitro. Biochem J 1 February 1975; 145 (2): 209–213. doi: https://doi.org/10.1042/bj1450209
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