Concanavalin A and Robinia pseudoacacia lectin decreased [3H]thymidine incorporation into acid-insoluble material of fibroblasts cultured from 6–10-day chick embryos. In contrast, these lectins stimulated [3H]thymidine incorporation in cells from 16-day embryos. These effects are due to neither [3H]thymidine permeability modification nor toxicity of the lectins. The specificity of lectin action was proved by blocking experiments with α-methyl mannopyranoside and with anti-(Robinia lectin) serum.

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