The copper-binding proteins with mol. wt. of approx. 12000 in the cytosol of pig liver have been identified as copper-thioneins. They contain variable amounts of zinc, with approx. 10% total metal in the protein. The molar cysteine/metal ratio is approx. 2:1.
Research Article|June 01 1976
Isolation of (copper, zinc-) thioneins from pig liver
Biochem J (1976) 155 (3): 631-635.
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I Bremner, B W Young; Isolation of (copper, zinc-) thioneins from pig liver. Biochem J 1 June 1976; 155 (3): 631–635. doi: https://doi.org/10.1042/bj1550631
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