The mol percentage of 5-hydroxymethylcytosine is 2.2 times greater in the adult than in 2-day-old rat brain DNA. The concentration of 5-hydroxymethylcytosine falls in corresponding liver DNA preparations. This normal increase in brain 5-hydroxymethylcytosine is abolished in rats placed on an 8%-protein diet 5 days after birth.
Research Article|June 01 1976
Modification of brain deoxyribonucleic acid base content with maturation in normal and malnourished rats
Biochem J (1976) 155 (3): 709-712.
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N W Penn; Modification of brain deoxyribonucleic acid base content with maturation in normal and malnourished rats. Biochem J 1 June 1976; 155 (3): 709–712. doi: https://doi.org/10.1042/bj1550709
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