1,4-Diaminobutanone, a competitive inhibitor of ornithine decarboxylase in Aspergillus nidulans, is able to increase the half-life of this enzyme and thus stimulate an increase in its activity in vivo. It also protects ornithine decarboxylase against proteolysis by chymotrypsin in vitro.
Research Article|September 15 1977
The effect of 1,4-diaminobutanone on the stability of ornithine decarboxylase from Aspergillus nidulans
Biochem J (1977) 166 (3): 635-637.
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L Stevens, I M McKinnon; The effect of 1,4-diaminobutanone on the stability of ornithine decarboxylase from Aspergillus nidulans. Biochem J 15 September 1977; 166 (3): 635–637. doi: https://doi.org/10.1042/bj1660635
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