Dihydropteridine reductase has been purified 900-fold from rat liver. Dopamine inhibited the enzyme up to 50% at a concentration of 0.11mm. In the presence of dopamine the enzyme gave non-hyperbolic v-against-[S] plots. This enzyme may have a role in control of dopamine biosynthesis.
Research Article|June 01 1981
Inhibition of dihydropteridine reductase by dopamine
Sheila E. Purdy;
John A. Blair;
Biochem J (1981) 195 (3): 769-771.
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Sheila E. Purdy, John A. Blair, Patricia A. Barford; Inhibition of dihydropteridine reductase by dopamine. Biochem J 1 June 1981; 195 (3): 769–771. doi: https://doi.org/10.1042/bj1950769
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