The requirement for net balance of synthesis, degradation and transport for all intermediates in the pathways from glucose to fat imposes constraints on the balance of fluxes between different pathways. Linear programming has been used to examine the interactions between these constraints on metabolism in adipocytes and the requirement for efficiency in the conversion of glucose into fat. The circumstances under which excessive ATP synthesis would accompany this conversion have been investigated.
Research Article|September 15 1986
Fat synthesis in adipose tissue. An examination of stoichiometric constraints
Biochem J (1986) 238 (3): 781-786.
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D A Fell, J R Small; Fat synthesis in adipose tissue. An examination of stoichiometric constraints. Biochem J 15 September 1986; 238 (3): 781–786. doi: https://doi.org/10.1042/bj2380781
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