Rat liver microsomes (microsomal fraction) were isolated from vitamin A-deficient and -sufficient rats and analysed for membrane lipid characteristics. Membrane fluidity was found to be significantly decreased in microsomes from the vitamin A-deficient rats, but not in liposomes prepared from lipid extracts. Microsomes from vitamin A-deficient animals showed a significant decrease in C18:2, omega 6 and an increase in C22:5, omega 6 fatty acids.
Research Article|August 01 1987
Liver microsomal membrane fluidity and lipid characteristics in vitamin A-deficient rats
M W Hamm;
Biochem J (1987) 245 (3): 907-910.
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M W Hamm, V Chan, G Wolf; Liver microsomal membrane fluidity and lipid characteristics in vitamin A-deficient rats. Biochem J 1 August 1987; 245 (3): 907–910. doi: https://doi.org/10.1042/bj2450907
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