In this study we investigated the structure of an acidic fucose-containing pentasaccharide released from bovine submaxillary-gland mucin by alkaline-borohydride treatment. The structure, determined by a combination of one-dimensional and two-dimensional 1H-n.m.r. spectroscopy at 270 MHz and methylation analysis involving g.l.c.-m.s., was as follows: Fuc alpha(1-2)Gal beta(1-4)GlcNAc beta(1-3)[NeuAc alpha(2-6)]GalNAcol This pentasaccharide is a novel structure and is the first report of a blood-group-H type 2 determinant on a submaxillary-gland mucin.
Determination of the structure of a novel acidic oligosaccharide with blood-group activity isolated from bovine submaxillary-gland mucin
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S M D'Arcy, C M Donoghue, C A M Koeleman, D H Van den Eijnden, A V Savage; Determination of the structure of a novel acidic oligosaccharide with blood-group activity isolated from bovine submaxillary-gland mucin. Biochem J 1 June 1989; 260 (2): 389–393. doi: https://doi.org/10.1042/bj2600389
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