Volume 400(2), pages 225–234

In Figure 5 of the original paper, the authors mistakenly duplicated some panels. The authors have repeated the experiment and a new Figure 5 is shown here.

AQP3 knockdown reduces EGF-induced AQP3 expression and cell migration in human skin fibroblasts.

Figure 5.
AQP3 knockdown reduces EGF-induced AQP3 expression and cell migration in human skin fibroblasts.

Cells were treated with EGF (100 ng/ml) and/or 100 nmol of AQP3 RNAi duplexes (more than four sequences) for 24 h. AQP3 expression in cell lysates was analyzed by Western blotting (A), blot results of three repeats were quantified (B). Cell migration was detected by phagokinetic track motility assay (C), and results were expressed as fold change vs. untreated control cells (“UNTR”) (D). Cell viability was tested by MTT assay (E, versus “UNTR” cells). The results represent means± S.E.M. For cell migration experiment, at least 50 cells' migration distance was counted for one condition (D). #P < 0.05 versus “UNTR”. *P < 0.05 versus EGF-treated cells.

Figure 5.
AQP3 knockdown reduces EGF-induced AQP3 expression and cell migration in human skin fibroblasts.

Cells were treated with EGF (100 ng/ml) and/or 100 nmol of AQP3 RNAi duplexes (more than four sequences) for 24 h. AQP3 expression in cell lysates was analyzed by Western blotting (A), blot results of three repeats were quantified (B). Cell migration was detected by phagokinetic track motility assay (C), and results were expressed as fold change vs. untreated control cells (“UNTR”) (D). Cell viability was tested by MTT assay (E, versus “UNTR” cells). The results represent means± S.E.M. For cell migration experiment, at least 50 cells' migration distance was counted for one condition (D). #P < 0.05 versus “UNTR”. *P < 0.05 versus EGF-treated cells.

Expression of Concern

The Editorial Board of the Biochemical Journal also have concerns with regard to Figures 1–3 and 5-7. The concerns relating to data and visualization for Figures 1–3 and 5–7 have been conveyed to the authors. The authors stand by the research in this manuscript. Unavailability of the original data has rendered further assessment impossible.