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Issues

Volume 441, Issue 3
February 2012
Biochemical Journal Cover Image for Volume 441, Issue 3
All Issues
ISSN 0264-6021
EISSN 1470-8728
In this Issue

Review articles

Glycogen and its metabolism: some new developments and old themes
Peter J. Roach; Anna A. Depaoli-Roach; Thomas D. Hurley; Vincent S. Tagliabracci
Biochem J (2012) 441 (3): 763–787.
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Ceramide synthases at the centre of sphingolipid metabolism and biology
Thomas D. Mullen; Yusuf A. Hannun; Lina M. Obeid
Biochem J (2012) 441 (3): 789–802.
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Research articles

The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities
Matthew Brook; Lora McCracken; James P. Reddington; Zhi-Liang Lu; Nicholas A. Morrice; Nicola K. Gray
Biochem J (2012) 441 (3): 803–816.
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Induction of oxidative stress, lysosome activation and autophagy by nanoparticles in human brain-derived endothelial cells
Blanka Halamoda Kenzaoui; Catherine Chapuis Bernasconi; Seher Guney-Ayra; Lucienne Juillerat-Jeanneret
Biochem J (2012) 441 (3): 813–821.
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Identification of persulfide-binding and disulfide-forming cysteine residues in the NifS-like domain of the molybdenum cofactor sulfurase ABA3 by cysteine-scanning mutagenesis
Markus Lehrke; Steffen Rump; Torsten Heidenreich; Josef Wissing; Ralf R. Mendel; Florian Bittner
Biochem J (2012) 441 (3): 823–839.
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The full-length Streptococcus pneumoniae major pilin RrgB crystallizes in a fibre-like structure, which presents the D1 isopeptide bond and provides details on the mechanism of pilus polymerization
Lamya El Mortaji; Carlos Contreras-Martel; Monica Moschioni; Ilaria Ferlenghi; Clothilde Manzano; Thierry Vernet; Andrea Dessen; Anne Marie Di Guilmi
Biochem J (2012) 441 (3): 833–843.
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α-Haemoglobin regulates sympathoadrenal cell metabolism to maintain a catecholaminergic phenotype
María T. Marcos-Almaraz; José A. Rodríguez-Gómez; José López-Barneo; Alberto Pascual
Biochem J (2012) 441 (3): 843–852.
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The p101 subunit of PI3Kγ restores activation by Gβ mutants deficient in stimulating p110γ
Aliaksei Shymanets; Mohammad R. Ahmadian; Katja T. Kössmeier; Reinhard Wetzker; Christian Harteneck; Bernd Nürnberg
Biochem J (2012) 441 (3): 851–858.
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Large T-antigen up-regulates Kv4.3 K+ channels through Sp1, and Kv4.3 K+ channels contribute to cell apoptosis and necrosis through activation of calcium/calmodulin-dependent protein kinase II
Qi Li; Ying Zhang; Yue Sheng; Rong Huo; Bo Sun; Xue Teng; Na Li; Jiu-Xin Zhu; Bao-Feng Yang; De-Li Dong
Biochem J (2012) 441 (3): 859–869.
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Detection of Rho GEF and GAP activity through a sensitive split luciferase assay system
Erik L. Anderson; Michael J. Hamann
Biochem J (2012) 441 (3): 869–880.
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Modulation of glucokinase by glucose, small-molecule activator and glucokinase regulatory protein: steady-state kinetic and cell-based analysis
Francis J. Bourbonais; Jing Chen; Cong Huang; Yanwei Zhang; Jeffrey A. Pfefferkorn; James A. Landro
Biochem J (2012) 441 (3): 881–887.
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Abi-1-bridged tyrosine phosphorylation of VASP by Abelson kinase impairs association of VASP to focal adhesions and regulates leukaemic cell adhesion
Masahiro Maruoka; Mizuho Sato; Yunfeng Yuan; Masayoshi Ichiba; Ryosuke Fujii; Takuya Ogawa; Norihiro Ishida-Kitagawa; Tatsuo Takeya; Naoki Watanabe
Biochem J (2012) 441 (3): 889–901.
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A mitochondrial-targeted cyclosporin A with high binding affinity for cyclophilin D yields improved cytoprotection of cardiomyocytes
Henry Dube; David Selwood; Sylvanie Malouitre; Michela Capano; Michela I. Simone; Martin Crompton
Biochem J (2012) 441 (3): 901–907.
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Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: implications for breast cancer progression
Newton J. Hurst, Jr; Abdo J. Najy; Carolyn V. Ustach; Lisa Movilla; Hyeong-Reh Choi Kim
Biochem J (2012) 441 (3): 909–919.
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BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1
Lisa Dohrn; Daniela Salles; Simone Y. Siehler; Julia Kaufmann; Lisa Wiesmüller
Biochem J (2012) 441 (3): 919–928.
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Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes
Roland Hjerpe; Yann Thomas; Jesse Chen; Aleksandra Zemla; Siobhan Curran; Natalia Shpiro; Lawrence R. Dick; Thimo Kurz
Biochem J (2012) 441 (3): 927–939.
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Thrombin-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein disulfide-isomerase
Mario Vallon; Philipp Aubele; Klaus-Peter Janssen; Markus Essler
Biochem J (2012) 441 (3): 937–944.
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Inactivation of mitochondrial aspartate aminotransferase contributes to the respiratory deficit of yeast frataxin-deficient cells
Dominika Sliwa; Julien Dairou; Jean-Michel Camadro; Renata Santos
Biochem J (2012) 441 (3): 945–953.
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Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation is associated with cell-type-dependent splicing of mtAspRS mRNA
Laura van Berge; Stephanie Dooves; Carola G.M. van Berkel; Emiel Polder; Marjo S. van der Knaap; Gert C. Scheper
Biochem J (2012) 441 (3): 955–962.
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LL37 and hBD-3 elevate the β-1,3-exoglucanase activity of Candida albicans Xog1p, resulting in reduced fungal adhesion to plastic
Hao-Teng Chang; Pei-Wen Tsai; Hsin-Hui Huang; Yu-Shu Liu; Tzu-Shan Chien; Chung-Yu Lan
Biochem J (2012) 441 (3): 963–970.
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Dynamic measurements of mitochondrial hydrogen peroxide concentration and glutathione redox state in rat pancreatic β-cells using ratiometric fluorescent proteins: confounding effects of pH with HyPer but not roGFP1
Leticia P. Roma; Jessica Duprez; Hilton K. Takahashi; Patrick Gilon; Andreas Wiederkehr; Jean-Christophe Jonas
Biochem J (2012) 441 (3): 971–978.
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Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration
Ning Xiao; Hui Li; Jian Luo; Rui Wang; Haiquan Chen; Jiquan Chen; Ping Wang
Biochem J (2012) 441 (3): 979–987.
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Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form
Genta Ito; Takeshi Iwatsubo
Biochem J (2012) 441 (3): 987–998.
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The adaptor protein 14-3-3 binds to the calcium-sensing receptor and attenuates receptor-mediated Rho kinase signalling
Ajanthy Arulpragasam; Aaron L. Magno; Evan Ingley; Suzanne J. Brown; Arthur D. Conigrave; Thomas Ratajczak; Bryan K. Ward
Biochem J (2012) 441 (3): 995–1007.
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Homo- and hetero-dimeric architecture of the human liver Na+-dependent taurocholate co-transporting protein
Ingrid T. G. W. Bijsmans; Rianne A. M. Bouwmeester; Joachim Geyer; Klaas Nico Faber; Stan F. J. van de Graaf
Biochem J (2012) 441 (3): 1007–1016.
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Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni2+ and Zn2+ reveals a role for the disordered C-terminal arm in metal trafficking
Katarzyna Banaszak; Vlad Martin-Diaconescu; Matteo Bellucci; Barbara Zambelli; Wojciech Rypniewski; Michael J. Maroney; Stefano Ciurli
Biochem J (2012) 441 (3): 1017–1035.
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