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Volume 443, Issue 1

April 2012

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Cover Image

Cover Image
Front Matter
Table of Contents
Editorial Board

ISSN 0264-6021

EISSN 1470-8728

In this Issue

Editorials
Review articles
Research articles
Correction articles

Editorials

How can we make publishing less painful?

Peter R. Shepherd

Biochem J (2012) 443 (1): 1.

Extract

View Articletitled, How can we make publishing less painful?

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Review articles

Antioxidant and bioenergetic coupling between neurons and astrocytes

Seila Fernandez-Fernandez; Angeles Almeida; Juan P. Bolaños

Biochem J (2012) 443 (1): 3–11.

Abstract

View Articletitled, Antioxidant and bioenergetic coupling between neurons and astrocytes

Supplementary data

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Replication fork dynamics and the DNA damage response

Rebecca M. Jones; Eva Petermann

Biochem J (2012) 443 (1): 13–26.

Abstract

View Articletitled, Replication fork dynamics and the DNA damage response

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Research articles

n−3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4⁺ T-cell activation

Tim Y. Hou; Jennifer M. Monk; Yang-Yi Fan; Rola Barhoumi; Yong Q. Chen; Gonzalo M. Rivera; David N. McMurray; Robert S. Chapkin

Biochem J (2012) 443 (1): 27–37.

Abstract

View Articletitled, n−3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4+ T-cell activation

Supplementary data

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The crystal structure of the Sox4 HMG domain–DNA complex suggests a mechanism for positional interdependence in DNA recognition

Ralf Jauch; Calista K. L. Ng; Kamesh Narasimhan; Prasanna R. Kolatkar

Biochem J (2012) 443 (1): 39–47.

Abstract

View Articletitled, The crystal structure of the Sox4 HMG domain–DNA complex suggests a mechanism for positional interdependence in DNA recognition

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Structure–function studies of a plant tyrosyl-DNA phosphodiesterase provide novel insights into DNA repair mechanisms of Arabidopsis thaliana

Hoyeun Kim; Sang Hyeon Na; So-Young Lee; Young-Min Jeong; Hyun-Ju Hwang; Jae Young Hur; Sang-Hyun Park; Je-Chang Woo; Sang-Gu Kim

Biochem J (2012) 443 (1): 49–56.

Abstract

View Articletitled, Structure–function studies of a plant tyrosyl-DNA phosphodiesterase provide novel insights into DNA repair mechanisms of Arabidopsis thaliana

Supplementary data

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The anti-neurodegenerative agent clioquinol regulates the transcription factor FOXO1a

Amy R. Cameron; Katherine Wallace; Lisa Logie; Alan R. Prescott; Terry G. Unterman; Jean Harthill; Graham Rena

Biochem J (2012) 443 (1): 57–64.

Abstract

View Articletitled, The anti-neurodegenerative agent clioquinol regulates the transcription factor FOXO1a

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A proximal pair of positive charges provides the dominant ligand-binding contribution to complement-like domains from the LRP (low-density lipoprotein receptor-related protein)

Peter G. W. Gettins; Klavs Dolmer

Biochem J (2012) 443 (1): 65–73.

Abstract

View Articletitled, A proximal pair of positive charges provides the dominant ligand-binding contribution to complement-like domains from the LRP (low-density lipoprotein receptor-related protein)

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Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death

Ayano Fukuhara; Mao Yamada; Ko Fujimori; Yuya Miyamoto; Toshihide Kusumoto; Hidemitsu Nakajima; Takashi Inui

Biochem J (2012) 443 (1): 75–84.

Abstract

View Articletitled, Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death

Supplementary data

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Distinct roles in folding, CD81 receptor binding and viral entry for conserved histidine residues of hepatitis C virus glycoprotein E1 and E2

Irene Boo; Kevin teWierik; Florian Douam; Dimitri Lavillette; Pantelis Poumbourios; Heidi E. Drummer

Biochem J (2012) 443 (1): 85–94.

Abstract

View Articletitled, Distinct roles in folding, CD81 receptor binding and viral entry for conserved histidine residues of hepatitis C virus glycoprotein E1 and E2

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Biochemical identification of the OsMKK6–OsMPK3 signalling pathway for chilling stress tolerance in rice

Guosheng Xie; Hideki Kato; Ryozo Imai

Biochem J (2012) 443 (1): 95–102.

Abstract

View Articletitled, Biochemical identification of the OsMKK6–OsMPK3 signalling pathway for chilling stress tolerance in rice

Supplementary data

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Serum copper as a novel biomarker for resistance to thyroid hormone

Jens Mittag; Thomas Behrends; Kristina Nordström; Joao Anselmo; Björn Vennström; Lutz Schomburg

Biochem J (2012) 443 (1): 103–109.

Abstract

View Articletitled, Serum copper as a novel biomarker for resistance to thyroid hormone

Supplementary data

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Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes

Catherine Arden; Susan J. Tudhope; John L. Petrie; Ziad H. Al-Oanzi; Kirsty S. Cullen; Alex J. Lange; Howard C. Towle; Loranne Agius

Biochem J (2012) 443 (1): 111–123.

Abstract

View Articletitled, Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes

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Autoinhibition mechanism of the plasma membrane calcium pump isoforms 2 and 4 studied through lipid–protein interaction

Irene C. Mangialavori; Gerardo Corradi; Débora E. Rinaldi; María Candelaria de la Fuente; Hugo P. Adamo; Juan Pablo F. C. Rossi

Biochem J (2012) 443 (1): 125–131.

Abstract

View Articletitled, Autoinhibition mechanism of the plasma membrane calcium pump isoforms 2 and 4 studied through lipid–protein interaction

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The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist

Kristy J. Wilson; Christopher P. Mill; Richard M. Gallo; Elizabeth M. Cameron; Henry VanBrocklin; Jeffrey Settleman; David J. Riese, II

Biochem J (2012) 443 (1): 133–144.

Abstract

View Articletitled, The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist

Supplementary data

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ROCKII Ser¹³⁶⁶ phosphorylation reflects the activation status

Hsiang-Hao Chuang; Chih-Hsuan Yang; Yeou-Guang Tsay; Chih-Yi Hsu; Ling-Ming Tseng; Zee-Fen Chang; Hsiao-Hui Lee

Biochem J (2012) 443 (1): 145–151.

Abstract

View Articletitled, ROCKII Ser1366 phosphorylation reflects the activation status

Supplementary data

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Transcriptional regulation mechanisms of hypoxia-induced neuroglobin gene expression

Ning Liu; Zhanyang Yu; Shuanglin Xiang; Song Zhao; Anna Tjärnlund-Wolf; Changhong Xing; Jian Zhang; Xiaoying Wang

Biochem J (2012) 443 (1): 153–164.

Abstract

View Articletitled, Transcriptional regulation mechanisms of hypoxia-induced neuroglobin gene expression

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Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation

Ana Luísa De Sousa-Coelho; Pedro F. Marrero; Diego Haro

Biochem J (2012) 443 (1): 165–171.

Abstract

View Articletitled, Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation

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The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α

Mark A. Barber; Annick Hendrickx; Monique Beullens; Hugo Ceulemans; David Oxley; Sylvia Thelen; Marcus Thelen; Mathieu Bollen; Heidi C. E. Welch

Biochem J (2012) 443 (1): 173–183.

Abstract

View Articletitled, The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α

Supplementary data

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Phosphate is not an absolute requirement for the inhibitory effects of cyclosporin A or cyclophilin D deletion on mitochondrial permeability transition

Allison M. McGee; Christopher P. Baines

Biochem J (2012) 443 (1): 185–191.

Abstract

View Articletitled, Phosphate is not an absolute requirement for the inhibitory effects of cyclosporin A or cyclophilin D deletion on mitochondrial permeability transition

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AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Laurent Bultot; Bruno Guigas; Alexander Von Wilamowitz-Moellendorff; Liliane Maisin; Didier Vertommen; Nusrat Hussain; Monique Beullens; Joan J. Guinovart; Marc Foretz; Benoît Viollet; Kei Sakamoto; Louis Hue; Mark H. Rider

Biochem J (2012) 443 (1): 193–203.

Abstract

View Articletitled, AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Supplementary data

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The yeast vacuolar Rab GTPase Ypt7p has an activity beyond membrane recruitment of the homotypic fusion and protein sorting–Class C Vps complex

Christopher Stroupe

Biochem J (2012) 443 (1): 205–211.

Abstract

View Articletitled, The yeast vacuolar Rab GTPase Ypt7p has an activity beyond membrane recruitment of the homotypic fusion and protein sorting–Class C Vps complex

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Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

Mingzhan Xue; Naila Rabbani; Hiroshi Momiji; Precious Imbasi; M. Maqsud Anwar; Neil Kitteringham; B. Kevin Park; Tomokazu Souma; Takashi Moriguchi; Masayuki Yamamoto; Paul J. Thornalley

Biochem J (2012) 443 (1): 213–222.

Abstract

View Articletitled, Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

Supplementary data

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The importance of an asymmetric distribution of acidic lipids for synaptotagmin 1 function as a Ca²⁺ sensor

Ying Lai; Yeon-Kyun Shin

Biochem J (2012) 443 (1): 223–229.

Abstract

View Articletitled, The importance of an asymmetric distribution of acidic lipids for synaptotagmin 1 function as a Ca2+ sensor

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New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries

Nunzianna Doti; Pasqualina L. Scognamiglio; Stefania Madonna; Claudia Scarponi; Menotti Ruvo; Giuseppe Perretta; Cristina Albanesi; Daniela Marasco

Biochem J (2012) 443 (1): 231–240.

Abstract

View Articletitled, New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries

Supplementary data

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The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD⁺

Gennaro Agrimi; Annamaria Russo; Pasquale Scarcia; Ferdinando Palmieri

Biochem J (2012) 443 (1): 241–247.

Abstract

View Articletitled, The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+

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Angiotensin II-dependent phosphorylation at Ser¹¹/Ser¹⁸ and Ser⁹³⁸ shifts the E₂ conformations of rat kidney Na⁺/K⁺-ATPase

Katherine J. Massey; Quanwen Li; Noreen F. Rossi; Raymond R. Mattingly; Douglas R. Yingst

Biochem J (2012) 443 (1): 249–258.

Abstract

View Articletitled, Angiotensin II-dependent phosphorylation at Ser11/Ser18 and Ser938 shifts the E2 conformations of rat kidney Na+/K+-ATPase

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Caveolae optimize tissue factor–Factor VIIa inhibitory activity of cell-surface-associated tissue factor pathway inhibitor

Susan A. Maroney; Paul E. Ellery; Jeremy P. Wood; Josephine P. Ferrel; Catherine E. Bonesho; Alan E. Mast

Biochem J (2012) 443 (1): 259–266.

Abstract

View Articletitled, Caveolae optimize tissue factor–Factor VIIa inhibitory activity of cell-surface-associated tissue factor pathway inhibitor

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Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms

Craigen R. Nes; Ujjal K. Singha; Jialin Liu; Kulothungan Ganapathy; Fernando Villalta; Michael R. Waterman; Galina I. Lepesheva; Minu Chaudhuri; W. David Nes

Biochem J (2012) 443 (1): 267–277.

Abstract

View Articletitled, Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms

Supplementary data

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Catalytic residues and a predicted structure of tetrahydrobiopterin-dependent alkylglycerol mono-oxygenase

Katrin Watschinger; Julian E. Fuchs; Vladimir Yarov-Yarovoy; Markus A. Keller; Georg Golderer; Albin Hermetter; Gabriele Werner-Felmayer; Nicolas Hulo; Ernst R. Werner

Biochem J (2012) 443 (1): 279–286.

Abstract

View Articletitled, Catalytic residues and a predicted structure of tetrahydrobiopterin-dependent alkylglycerol mono-oxygenase

Supplementary data

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Mechanism and specificity of the human paracaspase MALT1

Janna Hachmann; Scott J. Snipas; Bram J. van Raam; Erik M. Cancino; Emily J. Houlihan; Marcin Poreba; Paulina Kasperkiewicz; Marcin Drag; Guy S. Salvesen

Biochem J (2012) 443 (1): 287–295.

Abstract

View Articletitled, Mechanism and specificity of the human paracaspase MALT1

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Epithelial–mesenchymal interaction during UVB-induced up-regulation of neutral endopeptidase

Hiroaki Nakajima; Yoshiyuki Ezaki; Tomoyashu Nagai; Ryosuke Yoshioka; Genji Imokawa

Biochem J (2012) 443 (1): 297–305.

Abstract

View Articletitled, Epithelial–mesenchymal interaction during UVB-induced up-regulation of neutral endopeptidase

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Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex

Linda Troeberg; Barbara Mulloy; Peter Ghosh; Meng-Huee Lee; Gillian Murphy; Hideaki Nagase

Biochem J (2012) 443 (1): 307–315.

Abstract

View Articletitled, Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex

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A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier

Luis A. Luévano-Martínez; Carlos Barba-Ostria; Daniela Araiza-Olivera; Natalia Chiquete-Félix; Sergio Guerrero-Castillo; Eduardo Rial; Dimitris Georgellis; Salvador Uribe-Carvajal

Biochem J (2012) 443 (1): 317–325.

Abstract

View Articletitled, A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier

Supplementary data

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Correction articles

Structural stabilization of protein 4.1R FERM domain upon binding to apo-calmodulin: novel insights into the biological significance of the calcium-independent binding of calmodulin to protein 4.1R

W. Nunomura; D. Sasakura; K. Shiba; S. Nakamura; S.-i. Kidokoro; Y. Takakuwa

Biochem J (2012) 443 (1): 327.

Extract

View Articletitled, Structural stabilization of protein 4.1R FERM domain upon binding to apo-calmodulin: novel insights into the biological significance of the calcium-independent binding of calmodulin to protein 4.1R

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Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition

J.M. Martin-Garcia; J. Ruiz-Sanz; I. Luque

Biochem J (2012) 443 (1): 328.

Extract

View Articletitled, Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition

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Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

S. Pyr Dit Ruys; X. Wang; E. M. Smith; G. Herinckx; N. Hussain; M. H. Rider; D. Vertommen; C. G. Proud

Biochem J (2012) 443 (1): 328.

Extract

View Articletitled, Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

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