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Volume 450, Issue 1

February 2013

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Cover Image

Cover Image
Front Matter
Table of Contents
Editorial Board

ISSN 0264-6021

EISSN 1470-8728

In this Issue

Review articles
Research articles

Review articles

The dynamic nature of the kinome

Lee M. Graves; James S. Duncan; Martin C. Whittle; Gary L. Johnson

Biochem J (2013) 450 (1): 1–8.

Abstract

View Articletitled, The dynamic nature of the kinome

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Wnt/β-catenin signalling: from plasma membrane to nucleus

Wantae Kim; Minseong Kim; Eek-hoon Jho

Biochem J (2013) 450 (1): 9–21.

Abstract

View Articletitled, Wnt/β-catenin signalling: from plasma membrane to nucleus

Supplementary data

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Research articles

Novel configuration of a myosin II transient intermediate analogue revealed by quick-freeze deep-etch replica electron microscopy

Yoshitaka Kimori; Norio Baba; Eisaku Katayama

Biochem J (2013) 450 (1): 23–35.

Abstract

View Articletitled, Novel configuration of a myosin II transient intermediate analogue revealed by quick-freeze deep-etch replica electron microscopy

Supplementary data

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Kinetic analysis of Arabidopsis glucosyltransferase UGT74B1 illustrates a general mechanism by which enzymes can escape product inhibition

Jakub Kopycki; Elizabeth Wieduwild; Janine Kohlschmidt; Wolfgang Brandt; Anna N. Stepanova; Jose M. Alonso; M. Soledade C. Pedras; Steffen Abel; C. Douglas Grubb

Biochem J (2013) 450 (1): 37–46.

Abstract

View Articletitled, Kinetic analysis of Arabidopsis glucosyltransferase UGT74B1 illustrates a general mechanism by which enzymes can escape product inhibition

Supplementary data

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Parkinson's disease-associated human P_5B-ATPase ATP13A2 increases spermidine uptake

Diego P. De La Hera; Gerardo R. Corradi; Hugo P. Adamo; Felicitas De Tezanos Pinto

Biochem J (2013) 450 (1): 47–53.

Abstract

View Articletitled, Parkinson's disease-associated human P5B-ATPase ATP13A2 increases spermidine uptake

Supplementary data

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A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor

Aurélien Bidaud-Meynard; Daniela Arma; Said Taouji; Michel Laguerre; Jean Dessolin; Jean Rosenbaum; Eric Chevet; Violaine Moreau

Biochem J (2013) 450 (1): 55–62.

Abstract

View Articletitled, A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor

Supplementary data

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Probing the origins of glutathione biosynthesis through biochemical analysis of glutamate-cysteine ligase and glutathione synthetase from a model photosynthetic prokaryote

William B. Musgrave; Hankuil Yi; Dustin Kline; Jeffrey C. Cameron; Jonathan Wignes; Sanghamitra Dey; Himadri B. Pakrasi; Joseph M. Jez

Biochem J (2013) 450 (1): 63–72.

Abstract

View Articletitled, Probing the origins of glutathione biosynthesis through biochemical analysis of glutamate-cysteine ligase and glutathione synthetase from a model photosynthetic prokaryote

Supplementary data

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Interaction of amphiphysins with AP-1 clathrin adaptors at the membrane

Sonja Huser; Gregor Suri; Pascal Crottet; Martin Spiess

Biochem J (2013) 450 (1): 73–83.

Abstract

View Articletitled, Interaction of amphiphysins with AP-1 clathrin adaptors at the membrane

Supplementary data

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Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region

Deshun Gong; Fan Yang; Fudong Li; Dandan Qian; Minhao Wu; Zhenhua Shao; Mian Wu; Jihui Wu; Yunyu Shi

Biochem J (2013) 450 (1): 85–94.

Abstract

View Articletitled, Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region

Supplementary data

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The structure and properties of septin 3: a possible missing link in septin filament formation

Joci N. A. Macedo; Napoleão F. Valadares; Ivo A. Marques; Frederico M. Ferreira; Julio C. P. Damalio; Humberto M. Pereira; Richard C. Garratt; Ana P. U. Araujo

Biochem J (2013) 450 (1): 95–105.

Abstract

View Articletitled, The structure and properties of septin 3: a possible missing link in septin filament formation

Supplementary data

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Protein–protein interactions between the bilirubin-conjugating UDPglucuronosyltransferase UGT1A1 and its shorter isoform 2 regulatory partner derived from alternative splicing

Mélanie Rouleau; Pierre Collin; Judith Bellemare; Mario Harvey; Chantal Guillemette

Biochem J (2013) 450 (1): 107–114.

Abstract

View Articletitled, Protein–protein interactions between the bilirubin-conjugating UDPglucuronosyltransferase UGT1A1 and its shorter isoform 2 regulatory partner derived from alternative splicing

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Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P₆ and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation

Sabine Windhorst; Hongying Lin; Christine Blechner; Werner Fanick; Laura Brandt; Maria A. Brehm; Georg W. Mayr

Biochem J (2013) 450 (1): 115–125.

Abstract

View Articletitled, Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P6 and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation

Supplementary data

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Crystal structure of hexanoyl-CoA bound to β-ketoacyl reductase FabG4 of Mycobacterium tuberculosis

Debajyoti Dutta; Sudipta Bhattacharyya; Amlan Roychowdhury; Rupam Biswas; Amit Kumar Das

Biochem J (2013) 450 (1): 127–139.

Abstract

View Articletitled, Crystal structure of hexanoyl-CoA bound to β-ketoacyl reductase FabG4 of Mycobacterium tuberculosis

Supplementary data

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Role of Helicobacter pylori methionine sulfoxide reductase in urease maturation

Lisa G. Kuhns; Manish Mahawar; Joshua S. Sharp; Stéphane Benoit; Robert J. Maier

Biochem J (2013) 450 (1): 141–148.

Abstract

View Articletitled, Role of Helicobacter pylori methionine sulfoxide reductase in urease maturation

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Metal insertion into the molybdenum cofactor: product–substrate channelling demonstrates the functional origin of domain fusion in gephyrin

Abdel A. Belaidi; Guenter Schwarz

Biochem J (2013) 450 (1): 149–157.

Abstract

View Articletitled, Metal insertion into the molybdenum cofactor: product–substrate channelling demonstrates the functional origin of domain fusion in gephyrin

Supplementary data

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Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active

Sweta Maheshwari; Marina Lavigne; Alicia Contet; Blandine Alberge; Emilie Pihan; Clemens Kocken; Kai Wengelnik; Dominique Douguet; Henri Vial; Rachel Cerdan

Biochem J (2013) 450 (1): 159–167.

Abstract

View Articletitled, Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active

Supplementary data

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The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function

Veena Coothankandaswamy; Selvakumar Elangovan; Nagendra Singh; Puttur D. Prasad; Muthusamy Thangaraju; Vadivel Ganapathy

Biochem J (2013) 450 (1): 169–178.

Abstract

View Articletitled, The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function

Supplementary data

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Identification and properties of a novel variant of NBC4 (Na⁺/HCO₃⁻ co-transporter 4) that is predominantly expressed in the choroid plexus

Hidekazu Fukuda; Taku Hirata; Nobuhiro Nakamura; Akira Kato; Katsumasa Kawahara; Shigeo Wakabayashi; Min-Hwang Chang; Michael F. Romero; Shigehisa Hirose

Biochem J (2013) 450 (1): 179–187.

Abstract

View Articletitled, Identification and properties of a novel variant of NBC4 (Na+/HCO3− co-transporter 4) that is predominantly expressed in the choroid plexus

Supplementary data

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Ca²⁺ enhances Aβ polymerization rate and fibrillar stability in a dynamic manner

Kristoffer Brännström; Anders Öhman; Malin Lindhagen-Persson; Anders Olofsson

Biochem J (2013) 450 (1): 189–197.

Abstract

View Articletitled, Ca2+ enhances Aβ polymerization rate and fibrillar stability in a dynamic manner

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Differential configurations involving binding of USF transcription factors and Twist1 regulate Alx3 promoter activity in mesenchymal and pancreatic cells

Patricia García-Sanz; Antonio Fernández-Pérez; Mario Vallejo

Biochem J (2013) 450 (1): 199–208.

Abstract

View Articletitled, Differential configurations involving binding of USF transcription factors and Twist1 regulate Alx3 promoter activity in mesenchymal and pancreatic cells

Supplementary data

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Identification of novel signalling roles and targets for G_α and G_βγ downstream of the insulin-like growth factor 1 receptor in vascular smooth muscle cells

Raissa Perrault; Peter Zahradka

Biochem J (2013) 450 (1): 209–219.

Abstract

View Articletitled, Identification of novel signalling roles and targets for Gα and Gβγ downstream of the insulin-like growth factor 1 receptor in vascular smooth muscle cells

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FGF19 (fibroblast growth factor 19) as a novel target gene for activating transcription factor 4 in response to endoplasmic reticulum stress

Makoto Shimizu; Juan Li; Ryuto Maruyama; Jun Inoue; Ryuichiro Sato

Biochem J (2013) 450 (1): 221–229.

Abstract

View Articletitled, FGF19 (fibroblast growth factor 19) as a novel target gene for activating transcription factor 4 in response to endoplasmic reticulum stress

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Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes

Zoran Radić; Trevor Dale; Zrinka Kovarik; Suzana Berend; Edzna Garcia; Limin Zhang; Gabriel Amitai; Carol Green; Božica Radić; Brendan M. Duggan; Dariush Ajami; Julius Rebek, Jr; Palmer Taylor

Biochem J (2013) 450 (1): 231–242.

Abstract

View Articletitled, Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes

Supplementary data

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Human cytoplasmic ProX edits mischarged tRNA^Pro with amino acid but not tRNA specificity

Liang-Liang Ruan; Xiao-Long Zhou; Min Tan; En-Duo Wang

Biochem J (2013) 450 (1): 243–252.

Abstract

View Articletitled, Human cytoplasmic ProX edits mischarged tRNAPro with amino acid but not tRNA specificity

Supplementary data

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Review articles

The dynamic nature of the kinome

Wnt/β-catenin signalling: from plasma membrane to nucleus

Research articles

Novel configuration of a myosin II transient intermediate analogue revealed by quick-freeze deep-etch replica electron microscopy

Kinetic analysis of Arabidopsis glucosyltransferase UGT74B1 illustrates a general mechanism by which enzymes can escape product inhibition

Parkinson's disease-associated human P_5B-ATPase ATP13A2 increases spermidine uptake

A novel small-molecule screening strategy identifies mitoxantrone as a RhoGTPase inhibitor

Probing the origins of glutathione biosynthesis through biochemical analysis of glutamate-cysteine ligase and glutathione synthetase from a model photosynthetic prokaryote

Interaction of amphiphysins with AP-1 clathrin adaptors at the membrane

Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region

The structure and properties of septin 3: a possible missing link in septin filament formation

Protein–protein interactions between the bilirubin-conjugating UDPglucuronosyltransferase UGT1A1 and its shorter isoform 2 regulatory partner derived from alternative splicing

Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P₆ and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation

Crystal structure of hexanoyl-CoA bound to β-ketoacyl reductase FabG4 of Mycobacterium tuberculosis

Role of Helicobacter pylori methionine sulfoxide reductase in urease maturation

Metal insertion into the molybdenum cofactor: product–substrate channelling demonstrates the functional origin of domain fusion in gephyrin

Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active

The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function

Identification and properties of a novel variant of NBC4 (Na⁺/HCO₃⁻ co-transporter 4) that is predominantly expressed in the choroid plexus

Ca²⁺ enhances Aβ polymerization rate and fibrillar stability in a dynamic manner

Differential configurations involving binding of USF transcription factors and Twist1 regulate Alx3 promoter activity in mesenchymal and pancreatic cells

Identification of novel signalling roles and targets for G_α and G_βγ downstream of the insulin-like growth factor 1 receptor in vascular smooth muscle cells

FGF19 (fibroblast growth factor 19) as a novel target gene for activating transcription factor 4 in response to endoplasmic reticulum stress

Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes

Human cytoplasmic ProX edits mischarged tRNA^Pro with amino acid but not tRNA specificity

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