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Volume 453, Issue 1

July 2013

All Issues

Cover Image

Cover Image
Front Matter
Table of Contents
Editorial Board

ISSN 0264-6021

EISSN 1470-8728

In this Issue

Review articles
Research articles
Accelerated Publications
Correction articles
Commentaries

Review articles

The glyoxalase pathway: the first hundred years… and beyond

Marta Sousa Silva; Ricardo A. Gomes; Antonio E. N. Ferreira; Ana Ponces Freire; Carlos Cordeiro

Biochem J (2013) 453 (1): 1–15.

Abstract

View Articletitled, The glyoxalase pathway: the first hundred years… and beyond

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FilGAP and its close relatives: a mediator of Rho–Rac antagonism that regulates cell morphology and migration

Fumihiko Nakamura

Biochem J (2013) 453 (1): 17–25.

Abstract

View Articletitled, FilGAP and its close relatives: a mediator of Rho–Rac antagonism that regulates cell morphology and migration

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Research articles

New insights into the catalytic mechanism of histidine phosphatases revealed by a functionally essential arginine residue within the active site of the Sts phosphatases

Boris San Luis; Nicolas Nassar; Nick Carpino

Biochem J (2013) 453 (1): 27–35.

Abstract

View Articletitled, New insights into the catalytic mechanism of histidine phosphatases revealed by a functionally essential arginine residue within the active site of the Sts phosphatases

Supplementary data

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Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E

Stefan Mahrhold; Jasmin Strotmeier; Consuelo Garcia-Rodriguez; Jianlong Lou; James D. Marks; Andreas Rummel; Thomas Binz

Biochem J (2013) 453 (1): 37–47.

Abstract

View Articletitled, Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E

Supplementary data

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Lipin1 regulates PPARγ transcriptional activity

Hee Eun Kim; Eunju Bae; Deok-yoon Jeong; Min-Ji Kim; Won-Ji Jin; Sahng-Wook Park; Gil-Soo Han; George M. Carman; Eunjin Koh; Kyung-Sup Kim

Biochem J (2013) 453 (1): 49–60.

Abstract

View Articletitled, Lipin1 regulates PPARγ transcriptional activity

Supplementary data

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Evidence of a novel role for Pygopus in rRNA transcription

Phillip G. P. Andrews; Zhijian He; Youlian R. Tzenov; Catherine Popadiuk; Kenneth R. Kao

Biochem J (2013) 453 (1): 61–70.

Abstract

View Articletitled, Evidence of a novel role for Pygopus in rRNA transcription

Supplementary data

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Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity

Kate M. Dudek; Laura Suter; Veerle M. Darras; Emma L. Marczylo; Timothy W. Gant

Biochem J (2013) 453 (1): 71–82.

Abstract

View Articletitled, Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity

Supplementary data

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Zymogen activation of neurotrypsin and neurotrypsin-dependent agrin cleavage on the cell surface are enhanced by glycosaminoglycans

Claudio Gisler; Daniel Lüscher; Philipp Schätzle; Stephanie Dürr; Antonio Baici; Giovanna Galliciotti; Raymond Reif; Marc F. Bolliger; Beat Kunz; Peter Sonderegger

Biochem J (2013) 453 (1): 83–100.

Abstract

View Articletitled, Zymogen activation of neurotrypsin and neurotrypsin-dependent agrin cleavage on the cell surface are enhanced by glycosaminoglycans

Supplementary data

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Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

Paul Davies; Kelly M. Hinkle; Nour N. Sukar; Bryan Sepulveda; Roxana Mesias; Geidy Serrano; Dario R. Alessi; Thomas G. Beach; Deanna L. Benson; Charles L. White, III; Rita M. Cowell; Sonal S. Das; Andrew B. West; Heather L. Melrose

Biochem J (2013) 453 (1): 101–113.

Abstract

View Articletitled, Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

Supplementary data

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Phosphorylation of the guanine-nucleotide-exchange factor CalDAG-GEFI by protein kinase A regulates Ca²⁺-dependent activation of platelet Rap1b GTPase

Gianni Francesco Guidetti; Daria Manganaro; Alessandra Consonni; Ilaria Canobbio; Cesare Balduini; Mauro Torti

Biochem J (2013) 453 (1): 115–123.

Abstract

View Articletitled, Phosphorylation of the guanine-nucleotide-exchange factor CalDAG-GEFI by protein kinase A regulates Ca2+-dependent activation of platelet Rap1b GTPase

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Structural and functional interactions of the prostate cancer suppressor protein NKX3.1 with topoisomerase I

Liang-Nian Song; Cai Bowen; Edward P. Gelmann

Biochem J (2013) 453 (1): 125–136.

Abstract

View Articletitled, Structural and functional interactions of the prostate cancer suppressor protein NKX3.1 with topoisomerase I

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Ube2W conjugates ubiquitin to α-amino groups of protein N-termini

Michael H. Tatham; Anna Plechanovová; Ellis G. Jaffray; Helena Salmen; Ronald T. Hay

Biochem J (2013) 453 (1): 137–145.

Abstract

View Articletitled, Ube2W conjugates ubiquitin to α-amino groups of protein N-termini

Supplementary data

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Accelerated Publications

The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP

Dev Churamani; Robert Hooper; Taufiq Rahman; Eugen Brailoiu; Sandip Patel

Biochem J (2013) 453 (1): 147–151.

Abstract

View Articletitled, The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP

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Correction articles

Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)

G. M. Rahman; S. Shanker; N. E. Lewin; N. Kedei; C. S. Hill; B. V. V. Prasad; P. M. Blumberg; J. Das

Biochem J (2013) 453 (1): 153.

Extract

View Articletitled, Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)

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Aminolaevulinic acid synthase of Rhodobacter capsulatus: high-resolution kinetic investigation of the structural basis for substrate binding and catalysis

A.-L. Kaufholz; G. A. Hunter; G. C. Ferreira; T. Lendrihas; V. Hering; G. Layer; M. Jahn; D. Jahn

Biochem J (2013) 453 (1): 154.

Extract

View Articletitled, Aminolaevulinic acid synthase of Rhodobacter capsulatus: high-resolution kinetic investigation of the structural basis for substrate binding and catalysis

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ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours

M. L. Campos; V. J. Sánchez-Arévalo Lobo; A. Rodolosse; C. J. Gottardi; A. Mafficini; S. Beghelli; M. Scardoni; C. Bassi; A. Scarpa; F. X. Real

Biochem J (2013) 453 (1): 154.

Extract

View Articletitled, ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours

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Commentaries

N-terminal tagging of two-pore channels interferes with NAADP action

Andreas H. Guse

Biochem J (2013) 453 (1): e1–e2.

Abstract

View Articletitled, N-terminal tagging of two-pore channels interferes with NAADP action

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Macromolecular crowding and bicarbonate enhance the hydrogen peroxide-induced inactivation of glyceraldehyde-3-phosphate dehydrogenase

Editorial Note: Camelid single-domain antibodies raised by DNA immunization are potent inhibitors of EGFR signaling

Biochemical basis and therapeutic potential of mitochondrial uncoupling in cardiometabolic syndrome

Tweaking the redox properties of PpcA from Geobacter metallireducens with protein engineering

Opposed regulation of endoplasmic reticulum retention under stress by ERp44 and PDIA6

Review articles

The glyoxalase pathway: the first hundred years… and beyond

FilGAP and its close relatives: a mediator of Rho–Rac antagonism that regulates cell morphology and migration

Research articles

New insights into the catalytic mechanism of histidine phosphatases revealed by a functionally essential arginine residue within the active site of the Sts phosphatases

Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E

Lipin1 regulates PPARγ transcriptional activity

Evidence of a novel role for Pygopus in rRNA transcription

Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity

Zymogen activation of neurotrypsin and neurotrypsin-dependent agrin cleavage on the cell surface are enhanced by glycosaminoglycans

Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

Phosphorylation of the guanine-nucleotide-exchange factor CalDAG-GEFI by protein kinase A regulates Ca²⁺-dependent activation of platelet Rap1b GTPase

Structural and functional interactions of the prostate cancer suppressor protein NKX3.1 with topoisomerase I

Ube2W conjugates ubiquitin to α-amino groups of protein N-termini

Accelerated Publications

The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP

Correction articles

Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)

Aminolaevulinic acid synthase of Rhodobacter capsulatus: high-resolution kinetic investigation of the structural basis for substrate binding and catalysis

ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours

Commentaries

N-terminal tagging of two-pore channels interferes with NAADP action

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Research articles

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