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Volume 456, Issue 3
December 2013
Issue Cover
All Issues
ISSN 0264-6021
EISSN 1470-8728
In this Issue

Research articles

Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties
Alexander Wirth; Chen Chen-Wacker; Yao-Wen Wu; Nataliya Gorinski; Mikhail A. Filippov; Ghanshyam Pandey; Evgeni Ponimaskin
Biochem J (2013) 456 (3): 311–322.
View Articletitled, Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties
Supplementary data
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Defining the interaction of perforin with calcium and the phospholipid membrane
Daouda A. K. Traore; Amelia J. Brennan; Ruby H. P. Law; Con Dogovski; Matthew A. Perugini; Natalya Lukoyanova; Eleanor W. W. Leung; Raymond S. Norton; Jamie A. Lopez; Kylie A. Browne; Hideo Yagita; Gordon J. Lloyd; Annette Ciccone; Sandra Verschoor; Joseph A. Trapani; James C. Whisstock; Ilia Voskoboinik
Biochem J (2013) 456 (3): 323–335.
View Articletitled, Defining the interaction of perforin with calcium and the phospholipid membrane
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Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling
Simran S. Sabharwal; Gregory B. Waypa; Jeremy D. Marks; Paul T. Schumacker
Biochem J (2013) 456 (3): 337–346.
View Articletitled, Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling
Supplementary data
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Differential contribution of isoaspartate post-translational modifications to the fibrillization and toxic properties of amyloid β and the Asn23 Iowa mutation
Silvia Fossati; Krysti Todd; Krystal Sotolongo; Jorge Ghiso; Agueda Rostagno
Biochem J (2013) 456 (3): 347–360.
View Articletitled, Differential contribution of isoaspartate post-translational modifications to the fibrillization and toxic properties of amyloid β and the Asn<sup>23</sup> Iowa mutation
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A TFG–TEC nuclear localization mutant forms complexes with the wild-type TFG–TEC oncoprotein and suppresses its activity
Bobae Lim; Ah-young Kim; Hee Jung Jun; Jungho Kim
Biochem J (2013) 456 (3): 361–372.
View Articletitled, A TFG–TEC nuclear localization mutant forms complexes with the wild-type TFG–TEC oncoprotein and suppresses its activity
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A symptomatic Fabry disease mouse model generated by inducing globotriaosylceramide synthesis
Atsumi Taguchi; Hiroki Maruyama; Masaaki Nameta; Tadashi Yamamoto; Junichiro Matsuda; Ashok B. Kulkarni; Hidekatsu Yoshioka; Satoshi Ishii
Biochem J (2013) 456 (3): 373–383.
View Articletitled, A symptomatic Fabry disease mouse model generated by inducing globotriaosylceramide synthesis
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In vivo characterization of the properties of SUMO1-specific monobodies
Anja Berndt; Kevin A. Wilkinson; Michaela J. Heimann; Paul Bishop; Jeremy M. Henley
Biochem J (2013) 456 (3): 385–395.
View Articletitled, <em>In vivo</em> characterization of the properties of SUMO1-specific monobodies
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Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R-thiomandelic acid
Andreas Ioannis Karsisiotis; Christian F. Damblon; Gordon C. K. Roberts
Biochem J (2013) 456 (3): 397–407.
View Articletitled, Solution structures of the <em>Bacillus cereus</em> metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor <em>R</em>-thiomandelic acid
Supplementary data
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Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis
Thomas McQuade; YoungSik Cho; Francis Ka-Ming Chan
Biochem J (2013) 456 (3): 409–415.
View Articletitled, Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis
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Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells
Jonathan Barlow; Charles Affourtit
Biochem J (2013) 456 (3): 417–426.
View Articletitled, Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells
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Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle
Melissa E. Smith; Trevor S. Tippetts; Eric S. Brassfield; Braden J. Tucker; Adelaide Ockey; Adam C. Swensen; Tamil S. Anthonymuthu; Trevor D. Washburn; Daniel A. Kane; John T. Prince; Benjamin T. Bikman
Biochem J (2013) 456 (3): 427–439.
View Articletitled, Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle
Supplementary data
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The hydrogen-peroxide-induced radical behaviour in human cytochrome c–phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant
Badri S. Rajagopal; Ann N. Edzuma; Michael A. Hough; Katie L. I. M. Blundell; Valerian E. Kagan; Alexandr A. Kapralov; Lewis A. Fraser; Julea N. Butt; Gary G. Silkstone; Michael T. Wilson; Dimitri A. Svistunenko; Jonathan A. R. Worrall
Biochem J (2013) 456 (3): 441–452.
View Articletitled, The hydrogen-peroxide-induced radical behaviour in human cytochrome <em>c</em>–phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant
Supplementary data
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NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1
Janusz J. Petkowski; Lindsay A. Bonsignore; John G. Tooley; Daniel W. Wilkey; Michael L. Merchant; Ian G. Macara; Christine E. Schaner Tooley
Biochem J (2013) 456 (3): 453–462.
View Articletitled, NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1
Supplementary data
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Regulatory T-cells and cAMP suppress effector T-cells independently of PKA–CREM/ICER: a potential role for Epac
Amanda G. Vang; William Housley; Hongli Dong; Chaitali Basole; Shlomo Z. Ben-Sasson; Barbara E. Kream; Paul M. Epstein; Robert B. Clark; Stefan Brocke
Biochem J (2013) 456 (3): 463–473.
View Articletitled, Regulatory T-cells and cAMP suppress effector T-cells independently of PKA–CREM/ICER: a potential role for Epac
Supplementary data
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Correction articles

Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release
X. Tian; Y. Tang; Y. Liu; R. Wang; S. R. W. Chen
Biochem J (2013) 456 (3): 475.
View Articletitled, Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca<sup>2+</sup> release
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Reader's Choice

Autophagy: a two-edged sword in diabetes mellitus
Suguru Yamamoto; Junichiro J. Kazama; Masafumi Fukagawa
Biochem J (2013) 456 (3): e1–e3.
View Articletitled, Autophagy: a two-edged sword in diabetes mellitus
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