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May 2017
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Cover Image
Cover Image
Two isochorismate synthase enzymes, AtICS1 and AtICS2, are required for salicylic acid biosynthesis in Arabdopsis thaliana. This image shows the expression of AtICS1 (top) and AtICS2 (bottom) promoter-β-glucuronidase reporter gene constructs in mock inoculated (left) and cucumber mosaic virus infected (right) plants. AtICS1 is required for salicylic acid biosynthesis during host defense and has constitutive expression throughout the leaf that is induced by CMV infection. Constitutive expression of AtICS2 however, is confi ned to the vasculature and hydathodes and is unaffected by CMV infection. In this issue of the Biochemical Journal, Macaulay et al. (pages 1579–1590) explore the biochemical properties of the enzymes
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
How to win the HIV-1 drug resistance hurdle race: running faster or jumping higher?
Biochem J (2017) 474 (10): 1559–1577.
Research Articles
The biochemical properties of the two Arabidopsis thaliana isochorismate synthases
Keith M. Macaulay; Geraldine A. Heath; Alessio Ciulli; Alex M. Murphy; Chris Abell; John P. Carr; Alison G. Smith
Biochem J (2017) 474 (10): 1579–1590.
Structural basis of molecular recognition of helical histone H3 tail by PHD finger domains
Biochem J (2017) 474 (10): 1633–1651.
USP7 deubiquitinase controls HIV-1 production by stabilizing Tat protein
Biochem J (2017) 474 (10): 1653–1668.
Effect of position-specific single-point mutations and biophysical characterization of amyloidogenic peptide fragments identified from lattice corneal dystrophy patients
Venkatraman Anandalakshmi; Elavazhagan Murugan; Eunice Goh Tze Leng; Lim Wei Ting; Shyam S. Chaurasia; Toshio Yamazaki; Toshio Nagashima; Benjamin Lawrence George; Gary Swee Lim Peh; Konstantin Pervushin; Rajamani Lakshminarayanan; Jodhbir S. Mehta
Biochem J (2017) 474 (10): 1705–1725.
Roles of Leu28 side chain intercalation in the interaction between Cren7 and DNA
Biochem J (2017) 474 (10): 1727–1739.