October 2017
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
Targeting epithelial–mesenchymal plasticity in cancer: clinical and preclinical advances in therapy and monitoring
Biochemical Journal (1 October 2017) 474 (19): 3269–3306.
Regulating protein breakdown through proteasome phosphorylation
Biochemical Journal (1 October 2017) 474 (19): 3355–3371.
Research Articles
Activation of tissue plasminogen activator by metastasis-inducing S100P protein
Biochemical Journal (1 October 2017) 474 (19): 3227–3240.
Nitric oxide stimulates cellular degradation of human CYP51A1, the highly conserved lanosterol 14α-demethylase
Biochemical Journal (1 October 2017) 474 (19): 3241–3252.
Genetic human prion disease modelled in PrP transgenic Drosophila
Biochemical Journal (1 October 2017) 474 (19): 3253–3267.
Structural evidence of a phosphoinositide-binding site in the Rgd1-RhoGAP domain
Biochemical Journal (1 October 2017) 474 (19): 3307–3319.
Identification of drivers for the metamorphic transition of HIV-1 reverse transcriptase
Biochemical Journal (1 October 2017) 474 (19): 3321–3338.
Munc18a clusters SNARE-bearing liposomes prior to trans-SNARE zippering
Biochemical Journal (1 October 2017) 474 (19): 3339–3354.
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Cover Image
Cover Image
The 26S proteasome. Image kindly provided by Professor Joel Kowit from his work Degradation, a depiction in stained glass of the 26S proteasome (see http://joelkowit.com). In this issue of the Biochemical Journal, VerPlank and Goldberg describe how phosphorylation of the proteasome regulates protein breakdown by reviewing the ability of several kinases to alter proteasome function; see pages 3355–3371 for further details.
