The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human
A phosphatidic acid-binding protein is important for lipid homeostasis and adaptation to anaerobic biofilm conditions in Pseudomonas aeruginosa
The T4P-powered swarming of Myxococcus xanthus supported by a chimeric PilB of two bacterial origins. The bacterial type IV pilus (T4P) is a prevalent and versatile nanomachine with functions in bacterial locomotion and signal transduction as well as pathogenesis, biofilm formation and horizontal gene transfer. In this issue of the Biochemical Journal, Sukmana and Yang describe the complex steady-state kinetics of the T4P assembly motor ATPase PilB; for details, see pages 1979–1993.