DIS3 isoforms vary in their endoribonuclease activity and are differentially expressed within haematological cancers
Trade-offs with stability modulate innate and mutationally acquired drug resistance in bacterial dihydrofolate reductase enzymes
A digital illustration of lung cancer cells. In this issue of the Biochemical Journal, Windhorst et al. investigate the effect of the actin- and calcium-regulating activities of ITPKB on the metastatic potential of lung cancer cells; for details, see pages 2057–2071.