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Issues
September 2018
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Cover Image
Cover Image
In this issue of the Biochemical Journal, Thomas et al. report on the interaction between AMPK and one of its target proteins TBC1D1. The research shows that the association is AMPK-isoform-specific and that it is disrupted by a mutation linked to obesity. The cover image, taken from the article, shows Western blot analysis of the phosphorylation of transiently expressed GFP-TBC1D1 as well as AMPK and ACC from Flp-In HEK293 cells that stably express FLAG-AMPK-α1 or FLAG-AMPK-α2. For further details, see pages 2969–2983.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Research Articles
Isoproterenol-induced beta-2 adrenergic receptor activation negatively regulates interleukin-2 signaling
Biochem J (2018) 475 (18): 2907–2923.
Structure of the γ–ε complex of cyanobacterial F1-ATPase reveals a suppression mechanism of the γ subunit on ATP hydrolysis in phototrophs
Satoshi Murakami; Kumiko Kondo; Shinya Katayama; Satoshi Hara; Ei-ichiro Sunamura; Eiki Yamashita; Georg Groth; Toru Hisabori
Biochem J (2018) 475 (18): 2925–2939.
Chemical validation and optimization of pharmacoperones targeting vasopressin type 2 receptor mutant
Jo Ann Janovick; Timothy P. Spicer; Thomas D. Bannister; Emery Smith; Vadivel Ganapathy; Louis Scampavia
Biochem J (2018) 475 (18): 2941–2953.
IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD
Bea Unterer; Veit Wiesmann; Mekala Gunasekaran; Heinrich Sticht; Clara Tenkerian; Jürgen Behrens; Marina Leone; Felix B. Engel; Nathalie Britzen-Laurent; Elisabeth Naschberger; Thomas Wittenberg; Michael Stürzl
Biochem J (2018) 475 (18): 2955–2967.
Differential receptor selectivity of the FGF15/FGF19 orthologues determines distinct metabolic activities in db/db mice
Ann Maria K. Hansen; Sara G. Vienberg; Kirsten Lykkegaard; Xin Zhao; Guo Tingqing; Dan Han; Xujia Zhang; Henning Thøgersen; Kristian Sass-Ørum; Tina Tagmose; Kirsten Raun; Birgitte Andersen
Biochem J (2018) 475 (18): 2985–2996.
Mitochondrial-derived reactive oxygen species influence ADP sensitivity, but not CPT-I substrate sensitivity
Biochem J (2018) 475 (18): 2997–3008.
