November 2018
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
Chemical biology probes of mammalian GLUT structure and function
Biochemical Journal (30 November 2018) 475 (22): 3511–3534.
Insights into leptin signaling and male reproductive health: the missing link between overweight and subfertility?
Biochemical Journal (30 November 2018) 475 (22): 3535–3560.
Research Articles
Structural basis for the bi-functionality of human oxaloacetate decarboxylase FAHD1
Biochemical Journal (30 November 2018) 475 (22): 3561–3576.
The N-terminal domain of unknown function (DUF959) in collagen XVIII is intrinsically disordered and highly O-glycosylated
Biochemical Journal (30 November 2018) 475 (22): 3577–3593.
DDX3 directly facilitates IKKα activation and regulates downstream signalling pathways
Biochemical Journal (30 November 2018) 475 (22): 3595–3607.
The laterally acquired GH5 ZgEngAGH5_4 from the marine bacterium Zobellia galactanivorans is dedicated to hemicellulose hydrolysis
Biochemical Journal (30 November 2018) 475 (22): 3609–3628.
Exosomal KLF3-AS1 from hMSCs promoted cartilage repair and chondrocyte proliferation in osteoarthritis
Biochemical Journal (30 November 2018) 475 (22): 3629–3638.
Caffeine chelates calcium in the lumen of the endoplasmic reticulum
Biochemical Journal (30 November 2018) 475 (22): 3639–3649.
Two active site arginines are critical determinants of substrate binding and catalysis in MenD: a thiamine-dependent enzyme in menaquinone biosynthesis
Biochemical Journal (30 November 2018) 475 (22): 3651–3667.
Dimerization of the Trk receptors in the plasma membrane: effects of their cognate ligands
Biochemical Journal (30 November 2018) 475 (22): 3669–3685.
Potential role of a series of lysine-/leucine-rich antimicrobial peptide in inhibiting lipopolysaccharide-induced inflammation
Biochemical Journal (30 November 2018) 475 (22): 3687–3706.
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Cover Image
Cover Image
In this issue Moreira and colleagues provide insights into leptin signaling and male reproductive health and ask if leptin signaling is the missing link between obesity and subfertility. The cover image shows a representation of leptin signaling pathways. Circulating leptin bounds to the long isoform of leptin receptor (LepRb), which activates JAK2 tyrosine kinase, triggering a cascade of downstream signaling pathways. For further details, see pages 3535–3560.
