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Issues
November 2018
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Cover Image
Cover Image
In this issue Moreira and colleagues provide insights into leptin signaling and male reproductive health and ask if leptin signaling is the missing link between obesity and subfertility. The cover image shows a representation of leptin signaling pathways. Circulating leptin bounds to the long isoform of leptin receptor (LepRb), which activates JAK2 tyrosine kinase, triggering a cascade of downstream signaling pathways. For further details, see pages 3535–3560.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
Insights into leptin signaling and male reproductive health: the missing link between overweight and subfertility?
Biochem J (2018) 475 (22): 3535–3560.
Research Articles
Structural basis for the bi-functionality of human oxaloacetate decarboxylase FAHD1
Alexander K.H. Weiss; Andreas Naschberger; Johannes R. Loeffler; Hubert Gstach; Matthew W. Bowler; Max Holzknecht; Elia Cappuccio; Annabella Pittl; Solmaz Etemad; Theresia Dunzendorfer-Matt; Klaus Scheffzek; Klaus R. Liedl; Pidder Jansen-Dürr
Biochem J (2018) 475 (22): 3561–3576.
The N-terminal domain of unknown function (DUF959) in collagen XVIII is intrinsically disordered and highly O-glycosylated
Inderjeet Kaur; Salla Ruskamo; Jarkko Koivunen; Ritva Heljasvaara; Jarkko J. Lackman; Valerio Izzi; Ulla E. Petäjä-Repo; Petri Kursula; Taina Pihlajaniemi
Biochem J (2018) 475 (22): 3577–3593.
DDX3 directly facilitates IKKα activation and regulates downstream signalling pathways
Biochem J (2018) 475 (22): 3595–3607.
The laterally acquired GH5 ZgEngAGH5_4 from the marine bacterium Zobellia galactanivorans is dedicated to hemicellulose hydrolysis
Jonathan Dorival; Sophie Ruppert; Melissa Gunnoo; Adam Orłowski; Maylis Chapelais-Baron; Jérôme Dabin; Aurore Labourel; Damien Thompson; Gurvan Michel; Mirjam Czjzek; Sabine Genicot
Biochem J (2018) 475 (22): 3609–3628.
Exosomal KLF3-AS1 from hMSCs promoted cartilage repair and chondrocyte proliferation in osteoarthritis
Biochem J (2018) 475 (22): 3629–3638.
Caffeine chelates calcium in the lumen of the endoplasmic reticulum
Jonathan Rojo-Ruiz; Macarena Rodríguez-Prados; Alba Delrio-Lorenzo; María Teresa Alonso; Javier García-Sancho
Biochem J (2018) 475 (22): 3639–3649.
Two active site arginines are critical determinants of substrate binding and catalysis in MenD: a thiamine-dependent enzyme in menaquinone biosynthesis
Biochem J (2018) 475 (22): 3651–3667.
Dimerization of the Trk receptors in the plasma membrane: effects of their cognate ligands
Biochem J (2018) 475 (22): 3669–3685.
Potential role of a series of lysine-/leucine-rich antimicrobial peptide in inhibiting lipopolysaccharide-induced inflammation
Biochem J (2018) 475 (22): 3687–3706.