A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells
Tissue-specific characterization of mitochondrial branched-chain keto acid oxidation using a multiplexed assay platform
Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor
An acetylation mimicking mutation, K274Q, in tau imparts neurotoxicity by enhancing tau aggregation and inhibiting tubulin polymerization
Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb)
The cover image shows the oligomeric (upper) and filamentous (middle), and WT tau (left) and K274Q tau (right). The lower panels show toxicity of oligomeric tau on neuroblastoma cells. Rane and colleagues (pages 1401–1417) conclude that K274Q mutation enhances the oligomerization and filamentation of tau and these oligomers are toxic to neuroblastoma cells.