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Issues
May 2019
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Cover Image
Cover Image
The cover image shows the oligomeric (upper) and filamentous (middle), and WT tau (left) and K274Q tau (right). The lower panels show toxicity of oligomeric tau on neuroblastoma cells. Rane and colleagues (pages 1401–1417) conclude that K274Q mutation enhances the oligomerization and filamentation of tau and these oligomers are toxic to neuroblastoma cells.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Plastidic glucose-6-phosphate dehydrogenases are regulated to maintain activity in the light
Biochem J (2019) 476 (10): 1539–1551.
Multi-functional regulator MapZ controls both positioning and timing of FtsZ polymerization
Biochem J (2019) 476 (10): 1433–1444.
Screening substrate-binding positions by rolling circle amplification suggesting a binding model of Nt.BstNBI
Biochem J (2019) 476 (10): 1483–1496.
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells
Mam Y. Mboge; Zhijuan Chen; Daniel Khokhar; Alyssa Wolff; Lingbao Ai; Coy D. Heldermon; Murat Bozdag; Fabrizio Carta; Claudiu T. Supuran; Kevin D. Brown; Robert McKenna; Christopher J. Frost; Susan C. Frost
Biochem J (2019) 476 (10): 1497–1513.
Tissue-specific characterization of mitochondrial branched-chain keto acid oxidation using a multiplexed assay platform
Emma J. Goldberg; Katherine A. Buddo; Kelsey L. McLaughlin; Regina F. Fernandez; Andrea S. Pereyra; Christine E. Psaltis; Chien-Te Lin; James T. Hagen; Ilya N. Boykov; Tiffany K. Nguyen; Kymberly M. Gowdy; Jessica M. Ellis; P. Darrell Neufer; Joseph M. McClung; Kelsey H. Fisher-Wellman
Biochem J (2019) 476 (10): 1521–1537.
Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor
Biochem J (2019) 476 (10): 1419–1431.
Discerning the mechanism of action of HtrA4: a serine protease implicated in the cell death pathway
Biochem J (2019) 476 (10): 1445–1463.
Glycolic acid attenuates UVB-induced aquaporin-3, matrix metalloproteinase-9 expression, and collagen degradation in keratinocytes and mouse skin
Biochem J (2019) 476 (10): 1387–1400.
Designing active RNF4 monomers by introducing a tryptophan: avidity towards E2∼Ub conjugates dictates the activity of ubiquitin RING E3 ligases
Biochem J (2019) 476 (10): 1465–1482.
An acetylation mimicking mutation, K274Q, in tau imparts neurotoxicity by enhancing tau aggregation and inhibiting tubulin polymerization
Biochem J (2019) 476 (10): 1401–1417.
Structural basis for the C-domain-selective angiotensin-converting enzyme inhibition by bradykinin-potentiating peptide b (BPPb)
Edward D. Sturrock; Lizelle Lubbe; Gyles E. Cozier; Sylva L.U. Schwager; Afolake T. Arowolo; Lauren B. Arendse; Emma Belcher; K. Ravi Acharya
Biochem J (2019) 476 (10): 1553–1570.
