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October 2019
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Cover Image
Cover Image
Human zinc-α2-glycoprotein (ZAG) is a 42 kDa adipokine which regulates body fat mass and is associated with cachexia and obesity. In this issue Lau and colleagues (pp. 2815–2834) demonstrate an augmented mechanism for fatty acid binding in ZAG that is distinct from other known fatty acid binding proteins. On the cover co-crystallisation of the fat depleting factor ZAG (blue) with a lipid (white) reveals the presence of beta barrel tetramers which increase the lipid binding capacity of ZAG. Image created by Andy M. Lau.
ISSN 0264-6021
EISSN 1470-8728
In this Issue
Review Articles
Interactions between plants and soil shaping the root microbiome under abiotic stress
Biochem J (2019) 476 (19): 2705–2724.
Efficient photosynthesis in dynamic light environments: a chloroplast's perspective
Biochem J (2019) 476 (19): 2725–2741.
The plastid NAD(P)H dehydrogenase-like complex: structure, function and evolutionary dynamics
Biochem J (2019) 476 (19): 2743–2756.
Research Articles
Molecular, chemical, and structural characterization of prostaglandin A2 as a novel agonist for Nur77
Biochem J (2019) 476 (19): 2757–2767.
Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes
Biochem J (2019) 476 (19): 2769–2795.
Centrosomal cohesion deficits as cellular biomarker in lymphoblastoid cell lines from LRRK2 Parkinson's disease patients
Belén Fernández; Antonio Jesús Lara Ordóñez; Elena Fdez; Eugénie Mutez; Thomas Comptdaer; Coline Leghay; Alexandre Kreisler; Clémence Simonin; Laurine Vandewynckel; Luc Defebvre; Alain Destée; Séverine Bleuse; Jean-Marc Taymans; Marie-Christine Chartier-Harlin; Sabine Hilfiker
Biochem J (2019) 476 (19): 2797–2813.
Crystal structure of zinc-α2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding
Biochem J (2019) 476 (19): 2815–2834.
Calcium-induced dissociation of CIB1 from ASK1 regulates agonist-induced activation of the p38 MAPK pathway in platelets
Biochem J (2019) 476 (19): 2835–2850.
Coxiella burnetii utilizes both glutamate and glucose during infection with glucose uptake mediated by multiple transporters
Miku Kuba; Nitika Neha; David P. De Souza; Saravanan Dayalan; Joshua P. M. Newson; Dedreia Tull; Malcolm J. McConville; Fiona M. Sansom; Hayley J. Newton
Biochem J (2019) 476 (19): 2851–2867.
Membrane-associated RING-CH (MARCH) proteins down-regulate cell surface expression of the interleukin-6 receptor alpha chain (IL6Rα)
Jeffrey J. Babon; Dina Stockwell; Ladina DiRago; Jian-Guo Zhang; Artem Laktyushin; Jose Villadangos; Alan Ching; Satoshi Ishido; Douglas J. Hilton; Warren S. Alexander; Nicos A. Nicola
Biochem J (2019) 476 (19): 2869–2882.
Insulin and β-adrenergic receptors mediate lipolytic and anti-lipolytic signalling that is not altered by type 2 diabetes in human adipocytes
Biochem J (2019) 476 (19): 2883–2908.
Selective degradation of plasmid-derived mRNAs by MCPIP1 RNase
Yisong Qian; Xiuzhen Li; Ruidong Miao; Shufeng Liu; Hong-Bo Xin; Xiaotian Huang; Tony T. Wang; Mingui Fu
Biochem J (2019) 476 (19): 2927–2938.
