The transmembrane autophagy cargo receptors ATI1 and ATI2 interact with ATG8 through intrinsically disordered regions with distinct biophysical properties
Enhanced dynamics of conformationally heterogeneous T7 bacteriophage lysozyme native state attenuates its stability and activity
CGA-N9, an antimicrobial peptide derived from chromogranin A: direct cell penetration of and endocytosis by Candida tropicalis
MOV10 sequesters the RNP of influenza A virus in the cytoplasm and is antagonized by viral NS1 protein
Endothelin-converting enzyme-1 regulates glucagon-like peptide-1 receptor signalling and resensitisation
LHC-like proteins involved in stress responses and biogenesis/repair of the photosynthetic apparatus
In this issue, Leandrou et al. (pp 559–579) investigate activity of protein leucine-rich repeat kinase 2 (LRRK2) dimers. Kinase activity was notably different in mutant LRRK2 hetero- and homo-dimers. The cover image shows that de-phosphorylated and mutant LRRK2 cytoplasmic filaments are comprised of dimeric species. The image was supplied by Hardy J. Rideout.